Table 1.
Clinical features and outcome
| Case | sex/age | Cardiac surgery | Date surgery | Symptoms beginning | Date hospitali-zation | Micro-biological diagnosis (date) and disease history | Clinical syndromes | Medical therapy (mo) | Repeat surgery and disease history | Outcome |
| 1 | M 37 | CARR | 12/2012 TH | After 35 mo | 05/2016 | 09/2016, after 10 mo | PVE, AAP, DI | Anti-MAC (1) | After 8 mo | Deceased |
| 2 | M 60 | AVR + MVA | 01/2013 oH | After 40 mo | 05/2016 | 10/2016, after 11 mo | PVE, AAP, DI | No | No (see text) | Deceased |
| 3 | M 42 | AVR + ARR | 05/2015 TH | After 6 mo | 10/2016 | 11/2016, after 12 mo | PVE, AAP, DI | No | No | Deceased |
| 4 | M 75 | AVR | 02/2011 TH | After 64 mo | 07/2016 | 01/2017, after 7 mo | PVE, DI, SD | Anti-MAC (13) | After 15 mo | Deceased |
| 5 | M 80 | MVR + AW | 03/2016 TH | After 12 mo | 08/2018 | 09/2018, after 18 mo | PVE, SD | Targeted (14) | No | On therapy |
| 6 | M 56 | AVR | 06/2016 TH | After 27 mo | 11/2018 | 10/2018, after 1 mo | PVE, DI, SD | Targeted (12) | After 8 mo | On therapy |
| ARR | 05/2015 TH | |||||||||
| 7 | M 75 | AVR | 01/2014 oH | After 21 mo | 02/2019 | 04/2019, after 8 months | PVE | Targeted (4) | No | On therapy |
| AVR | 11/2016 oH | |||||||||
| 8 | M 76 | AVR + CABG | 02/2011 TH | After 97 mo | 05/2019 | 05/2019, after 2 mo | PVE, DI, SD | Targeted (3) | No | On therapy |
| 9 | M 82 | AVR + CABG | 08/2016 oH | After 12 mo | 06/2019 | 06/2019, after 22 mo | PVE | Targeted (2) | No | On therapy |
AAP: Ascending aortic pseudoaneurysm; ARR: Aortic root replacement; AVR: Aortic valve replacement; AW: Ascending aortic wrapping; CABG: Coronary artery bypass graft; cARR: Composite aortic root replacement; DI: Disseminated infection; MVA: Mitral valve annuloplasty; oH: Other hospital; PVE: Prosthetic valve endocarditis; SD: Spondylodiscitis; TH: Treviso Hospital; MAC: Mycobacterium avium complex.