Table 2.
Clinical features of Mycobacterium chimaera infections and selected laboratory abnormalities of Mycobacterium chimaera infected patients at presentation in United Kingdom and Treviso patients (modified, from Scriven et al[16], 2018)
| Variable | UK patients (n = 30) | Italian patients (n = 9) |
| Clinical finding, n (%) | ||
| Fever | 24 (80) | 7 (78) |
| Malaise (astenia) | 24 (80) | 7 (78) |
| Weight loss | 18 (60) | 6 (66) |
| Cough | 11 (37) | 3 (33) |
| Dyspnoea | 10 (33) | 2 (22) |
| Arthralgia | 6 (20) | 0 |
| Chest pain | 6 (20) | 0 |
| Abdominal pain | 3 (10) | 0 |
| Back pain | 2 (7) | 5 (55) |
| New cardiac murmur | 9 (30) | 6 (66) |
| Oedema | 6 (20) | 1 (11) |
| Crepitations | 6 (20) | 0 |
| Splenomegaly | 8 (27) | 6 (66) |
| Hepatomegaly | 6 (20) | 3 (33) |
| Lymphadenopathy | 1 (3) | 1 (11) |
| Sternal wound | 4 (13) | 0 |
| Skin lesion | 2 (7) | 0 |
| Choroiditis | 2 (7) | 5 (55) |
| Neurological symptoms | NA | 5 (55) |
| Laboratory findings, median (IQR) | ||
| Haemoglobin (g/L) | 110 (96-127) | 105 (95-114) |
| WBC (× 109/L) | 3.9 (2.2-5.4) | 3.9 (2.8-6.7) |
| Neutrophils (× 109/L) | 2.4 (1.3-3.3) | 2.6 (1.4-3.8) |
| Lymphocytes (× 109/L) | 0.9 (0.6-1.3) | 0.76 (0.56–1.05) |
| Platelets (× 109/L) | 175 (86-223) | 166 (76-257) |
| Albumin (g/L) | 30 (26-37) | 34 (27-39) |
| ALT (IU/L) | 43 (33-85) | 41 (15-70) |
| ALP (IU/L) | 256 (132-357) | 242 (157-254) |
| Sodium (µmol/L) | 134 (131-136) | 131 (128-136) |
| eGFR (mL/min) | 66 (53-80) | 52 (35-81) |
| CRP (mg/L) | 33 (17-46) | 19 (14-31) |
| ESR (mm/h) | NA | 65 (36-111) |
| LDH (IU/L) | NA | 463 (244-680) |
| gammaGT (IU/L) | NA | 104 (44-156) |
ALP: Alkaline phosphatase; ALT: Alanine transaminase; CRP: C-reactive protein; eGFR: Estimated glomerular filtration rate; ESR: Erythrocyte sedimentation rate; gammaGT: Gammaglutamiltranspeptidase; IQR: Interquartile range; LDH: Lactate dehydrogenase; NA: Not available; WBC: White blood count.