Table 1.
Vaccine treatment groups and vaccine formulations.
| Groups | Adjuvant Composed | Strains | Others Antigens |
|---|---|---|---|
| Vaccine A (n = 9) | Aluminum hydroxide (Alhydrogel®) | Bovine viral diarrhea virus (BVDV)-1 (Singer) and BVDV-2 inactivated, strains from INTA 1 and CEVAN 2; bovine herpesvirus 1 (BHV)-1 (Los Angeles) inactivated |
Campylobacter fetus; Campylobacter fetus veneralis; Leptospira interrogans pomona; Histophilus somni. |
| Vaccine B (n = 10) | Oil-in-water adjuvant (mineral oil-based) | BVDV-1 and BVDV 2 (inactivated); BHV-1 and BoHV-5 (inactivated) | Leptospirahardjo, L. icterohaemorrhagiae, L. Bratislava, L. Pomona and L. wolfi |
| Vaccine C (n = 10) | Amphigen and Quil A cholesterol and dimethyl dioctadecylammonium (DDA) bromide (QAD) adjuvant ® | BVDV-1 (5960) and BVDV-2 (53,637) inactivated; BHV-1 (RBL106) thermosensitive | Leptospira canicola, L. grippotyphosa, L. hardjo, L. icterohaemorrhagiae and L. pomona |
| Control (n = 6) | - | Saline Solution | - |
1 INTA=Instituto Nacional de Tecnología Agropecuaria, Argentina; 2 CEVAN = Centro de Virología Animal, Argentina, BVDV = Bovine Viral Diarrhea Virus, BHV-1 = bovine herpesvirus type 1.