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. 2019 Jul 4;9(3):57. doi: 10.3390/life9030057

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Percentage depurination is plotted against time for estimating the degradation of AMP under reaction conditions used for dehydration-rehydration (DH-RH) reactions. AMP gets degraded to about half of the starting concentration in ~6.35 h at pH 2 and 90 °C. (n = 3, R² = 0.9941).