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. 2019 Jul 29;6(3):81. doi: 10.3390/medicines6030081

Figure 4.

Figure 4

A. lappa extract reduces tumor growth and rescues animal mortality. (A) For assessment of tumor size and (B) mice survival, B16F10 melanoma cells were implanted and the animals received Alhe (50 mg/kg/300 μL) or PBS (300 μL) every 5 days for 30 days. (A) Tumors were measured with a Vernier caliper, and tumor volume was calculated with the equation—tumor length × height × width/2. (B) Animal survival was monitored for 30 days. The experiment was conducted twice using five mice per group (n = 5). Data denote mean ± SEM. * Tumor versus tumor + A. lappa. Differences were considered significant with p < 0.05, according to ANOVA with Tukey’s post-test (tumor growth) or the log-rank test (mice survival).