Table 1.

Recurrent copy number alterations observed in prostate cancers (data reported in Refs. [78,79]).

Chromosome Region	Genetic Event	Genes Involved	Frequency in Primary Tumors (%)	Frequency in Advanced Tumors (%)
2q	Deletion	CXCR4	23	61
3p13	Deletion	FOXP1, RYBP, SQQ1	20	32
5q	Deletion	CHD1, APC	36	76
6q	Deletion	MAP3K7, ZNF292	41	74
8p	Deletion	NKX3-1, PPP2B2A	56	90
10q	Deletion	PTEN	26	83
12p	Deletion	CDKN1B	24	53
13q	Deletion	BRCA2, RB1	45	90
16q	Deletion	CDH1	44	90
17p	Deletion	TP53	28	78
17q	Deletion	BRCA1, ETV4	17	41
18q	Gain	SMAD4, BCL2	25	67
3q	Gain	PI3KCA, ETV5	10	61
7	Gain	ETV1, EGFR, MCM7, BRAF	14	75
8q	Gain	MYC	21	84
16p	Gain	-	18	64
21q	Fusion	ERG, TMPRSS2	25	48