Autocrine signaling of TNF-α, IL-1α, and IL-1β amplifies the secretion of the proinflammatory cytokine IL-6 and the chemokines CXCL8 and CCL5 following RSV infection (A); Primary airway epithelial cells and airway epithelial cell lines secrete chemokines at different time points throughout the course of RSV infection as outlined in Table 1. The chemokines facilitate the recruitment of innate immune cells from the periphery to the lung where they implement antiviral actions through various cell-specific mechanisms (B). Major Basic Protein (MBP), Eosinophil Cationic Protein (ECP), Eosinophil-derived neurotoxin (EDN), Myeloperoxidase (MPO), reactive oxygen species (ROS).