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Wnt activation after lethal whole-abdomen irradiation mitigates radiation-induced gastrointestinal lethality. (A) Kaplan–Meier survival curve comparing shControl and shApc hairpin induction after 14.5 Gy WAI (n ≥ 2 per group, with ≥2 experimental replicates). (B) Fourteen-day mortality with escalating WAI RT dose in shControl and shApc mice (n ≥ 3 per group). A, Log-rank comparison.
