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Concentration-response curves of chlorogenic acids from the fundus, ileum, and colon isolated from guinea pig. Test substances were applied to organs after a stabilization period. Values represent the exchange of isolated organ tension compared to before dimethyl sulfoxide (DMSO) application. Mean represents mean ± SEM of the contraction normalized to 20 µM acetylcholine (ACh) in the fundus and 0.2 µM ACh in the ileum and colon. *p < 0.05 and **p < 0.01 to DMSO by Dunnett’s test.
