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. 2019 Jul 18;4(3):108. doi: 10.3390/tropicalmed4030108

Table 3.

Guidelines for treatment of filarial parasite infections through preventive chemotherapy mass drug administration campaigns.

Disease Areas not Co-endemic with Onchocerciasis Areas Co-endemic with Onchocerciasis Areas Co-endemic with Loiasis
Onchocer-ciasis ivermectin (150–200 µg/kg) not advised; test and not treat strategies investigated
Lymphatic filariasis once a year DEC (6 mg/kg) and albendazole (400 mg); 2018–2019 start triple therapy in select countries once a year ivermectin (200 µg/kg) with albendazole (400 mg) twice a year albendazle (400 mg)
Loiasis DEC or albendazole; treatment not always recommended due to risk of SAEs; no programs currently in place to control or eliminate loiasis

DEC, diethylcarbamazine citrate; SAEs, severe adverse events.