Table A2.

Oral clarithromycin desensitization protocol in an adult [100] *.

Dose No.	Concentration (mg/mL)	Dose
		mL	mg
1.	0.025	1.25	0.030
2.	0.025	2.50	0.060
3.	0.025	5	0.125
4.	0.250	1	0.250
5.	0.250	2	0.5
6.	0.250	4	1
7.	2.5	0.8	2
8.	2.5	1.6	4
9.	2.5	3.2	8
10.	2.5	6.4	16
11.	25	1.3	32
12.	25	2.5	64
13.	25	5	125
14.	25	10	250
Cumulative dose			503

Abbreviations: mg = milligrams; mL = milliliters; no = number. * Serial 10-fold dilutions of a clarithromycin suspension of 125 mg/5 mL (25 mg/mL) were performed to make clarithromycin solutions at 2.5, 0.25, and 0.025 mg/mL. Each dose was administered in 15-min intervals over 3.5 h.