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. 2019 Jul 9;9(3):59. doi: 10.3390/life9030059

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Chemical structure of the representative formulation materials, including (A) lipids, (B) polymers and (C) peptides. Abbreviations: DOTAP: 1,2-dioleoyl-3trimethylammonium-propane; DOPE: dioleoylphosphatidyl ethanolamine; CHEMS: cholesteryl hemisuccinate; DC-cholesterol: 3β-[N-(dimethylaminoethane)carbamoyl] cholesterol; DOSPA: 2,3-dioleyloxy-N-[2(sperminecarboxamido)ethyl]-N,N-dimethyl-1-propanaminium trifluoroacetate; PEG: polyethylene glycol; PEI: polyethylenimine; CPP: cell penetrating peptide; SV40: simian virus 40; NLS: nuclear localization signal; HA2: hemagglutinin 2.