Table 1.
Baseline patient characteristics
| Characteristics | Overall cohort (n = 100) |
|---|---|
| Age at surgery (years) | 71 [63, 75] |
| Female gender | 34 (34%) |
| Body mass index (kg/m2) | 27 [25, 32] |
| NYHA Functional class ≥ III | 16 (16%) |
| Cardiovascular risk factors | |
| Dyslipidemia | 18 (18%) |
| Hypertension | 54 (54%) |
| Diabetes mellitus | 19 (19%) |
| Chronic obstructive pulmonary disease | 12 (12%) |
| Peripheral vascular disease | 5 (5.0%) |
| Previous cerebrovascular accident | 9 (9.0%) |
| Previous transient ischemic attack | 8 (8.0%) |
| Atrial fibrillation | 22 (22%) |
| Severely renal impairment (CC ≤ 50) | 3 (3.0%) |
| Previous history of percutaneous coronary intervention | 10 (10%) |
| Logistic EuroSCORE I | 4.3 [2.9, 6.3] |
| Pre-operative echocardiography | |
| Left ventricular function | |
| Mild dysfunction (LVEF 30–50%) | 10 (10%) |
| Peak aortic transvalvular gradient (mmHg) | 73 ± 22 |
| Aortic Valve Area (cm2) | 0.8 ± 0.2 |
| Aortic valve pathology | |
| Severe aortic stenosis | 84 (84%) |
| Aortic insufficiency grade ≥ III | 4 (4.0%) |
| Aortic stenosis and insufficiency grade ≥ III | 2 (2.0%) |
| Bicuspid aortic valve (BAV) | 30 (30%) |
Results are expressed as mean ± standard deviation, median [IQR: 25th, 75th percentile] or frequency (%). CC Creatine clearance, EuroSCORE European System for Cardiac Operative Risk Evaluation, LVEF Left ventricular ejection fraction, NYHA New York Heart Association