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. 2019 Oct 8;12:2053–2064. doi: 10.2147/DMSO.S213400

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© 2019 Sun et al.

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Effect of exosomes (Exo) on streptozotocin (STZ)-induced diabetic mice.

Notes: Male C57 mice were administrated with high-dose of STZ (200mg/kg), and Exo was transplanted afterwards. (A) Non-fasting blood glucose levels, (B) survival time, (C) body weight, (D) serum insulin and (E) insulin content extract from pancreas were compared. Data were showed as mean ± SEM. *P<0.05, **P<0.01, ***P<0.001, between indicated groups (Control, n=3; STZ, n=5; STZ+Exo, n=11).

Abbreviations: Exo, exosomes; STZ, streptozotocin.