Table 4.
Sensitivity, specificity, efficiency, and 95% confidence intervals for Stage 1 of PBS and IBS at various cutoffs.
| Candidate tests | Cutoff | Sensitivity | Specificity | Proportion who screen positive (efficiency) |
|---|---|---|---|---|
| Patient Based Screening (PBS): Stage 1 | ||||
| Memory Impairment Screen (MIS) | ≤4 | 32 (21,44) | 94 (89,97) | 13 (9,18) |
| ≤5 | 47 (35,60) | 90 (85,94) | 20 (15,25) | |
| ≤6 | 70 (57,80) | 76 (69,82) | 36 (30,42) | |
| Animal Fluency (AF) | ≤9 | 42 (30,55) | 84 (78,89) | 23 (18,28) |
| ≤10 | 48 (36,61) | 75 (69,81) | 31 (25,37) | |
| Months Backwards (MB) | ≥1 | 73 (60,83) | 57 (50,64) | 51 (44,57) |
| ≥2 | 65 (52,76) | 69 (61,75) | 40 (34,46) | |
| MIS<=5 or MB>=2 | ----- | 79 (67,88) | 65 (58,72) | 46 (40,53) |
| MIS<=5 or AF<=9 | ----- | 68 (56,79) | 69 (62,76) | 40 (34,47) |
| MIS<=5 or MB>=2 or AF<=9 | ----- | 88 (78,95) | 58 (50,65) | 54 (48,60) |
| Informant Based Screening (IBS): Stage 1 | ||||
| IQCODE | ≥3.1 | 97(89,100) | 64 (56,71) | 52 (46,58) |
| ≥3.2 | 94 (85,98) | 79 (72,85) | 40 (34,46) | |
| ≥3.3 | 88 (78,95) | 88 (83,93) | 31 (26,37) | |
| ≥3.4 | 82 (70,90) | 92 (87,96) | 27 (22,33) | |