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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Phytomedicine. 2019 Apr 12;64:152927. doi: 10.1016/j.phymed.2019.152927

Figure 7. Protective efficacy and functional antibody responses in male ferrets immunized with squalene or polyprenol nanoemulsions.

Figure 7.

(a) Percent survival after a single immunization followed by intranasal challenge 21-days post immunization with A/Vietnam/1203/04. (b) Average normalized change in body weight following challenge. (c) Average clinical score following challenge. (d) Average change in temperature following challenge. (e) Geometric mean (+/− geometric s.d.) virus titer detected in nasal washes following challenge. (f-h) Geometric mean (+/− geometric s.d.) of virus neutralizing antibodies to homologous or heterologous strains measured 21 days after immunization using a retrovirus pseudotype neutralization assay.