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. 2019 May 10;42(11):1319–1327. doi: 10.1007/s40618-019-01055-0

Table 2.

Comparison of the rate of malignancy determined by postoperative histopathological examination in HC and non-HC nodules in relation to the category of FNA result*,**

Category of FNA results Results of histopathological examinations—No/% of patients p
HC smears Non-HC smears
Benign Malignant Benign Malignant
Last FNA before Bethesda classification—2005–2009
 II 89/95.6 4/4.3 875/99.4 5/0.6 0.0026
 III 4/100.0 19/100.0
 IV 53/91.4 5/8.6 67/90.5 7/9.5 0.8679
 V 6/85.7 1/14.3 33/84.6 6/15.4 0.6193
 VI 3/100 3/5.4 53/94.6 0.3486
 Total 152/92.1 13/7.9 997/93.4 71/6.6 0.5592
Last FNA after Bethesda classification—2010–2017
 II 54/98.2 1/1.8 1184/99.2 9/0.8 0.9269
 III 28/90.3 3/9.7 204/96.2 8/3.8 0.3104
 IV 69/87.3 10/12.7 57/89.1 7/10.9 0.7519
 V 7/58.3 5/41.7 28/41.8 39/58.2 0.2881
 VI 8/100 4/3.1 124/96.9 0.5680
 Total 158/85.4 27/14.6 1477/88.8 187/11.2 0.1758

*When several FNA were performed in a patient, the outcome of the last one was considered

**Statistical analysis did not include incidental cancers