Table 1.
Variables | All Participants(n = 115) | No Arterial StiffnessGroup (n = 74) | High Arterial StiffnessGroup (n = 41) | P value |
---|---|---|---|---|
Age (years) | 65.61 ± 8.97 | 63.38 ± 8.57 | 69.63 ± 8.32 | < 0.001* |
Height (cm) | 161.21 ± 8.08 | 161.53 ± 7.41 | 160.63 ± 9.23 | 0.572 |
Body weight (kg) | 68.31 ± 11.84 | 67.41 ± 11.63 | 69.94 ± 12.17 | 0.273 |
Waist circumference (cm) | 93.08 ± 9.75 | 91.50 ± 9.41 | 95.93 ± 9.82 | 0.019* |
Body mass index (kg/m2) | 26.19 ± 3.45 | 25.73 ± 3.34 | 27.03 ± 3.53 | 0.053 |
cfPWV (m/s) | 9.52 ± 2.60 | 8.11 ± 1.59 | 12.06 ± 2.09 | < 0.001* |
Systolic blood pressure (mmHg) | 132.04 ± 18.14 | 127.72 ± 15.50 | 139.85 ± 20.05 | < 0.001* |
Diastolic blood pressure (mmHg) | 72.55 ± 10.28 | 71.74 ± 10.32 | 74.00 ± 10.18 | 0.261 |
Total cholesterol (mg/dL) | 165.67 ± 35.19 | 137.32 ± 35.87 | 162.68 ± 34.17 | 0.501 |
Triglycerides (mg/dL) | 121.00 (90.00–166.00) | 115.00 (89.00–184.25) | 127.00 (90.50–152.50) | 0.829 |
HDL-C (mg/dL) | 44.92 ± 11.95 | 46.41 ± 11.79 | 42.24 ± 11.92 | 0.074 |
LDL-C (mg/dL) | 95.83 ± 26.53 | 96.08 ± 25.31 | 95.37 ± 28.93 | 0.891 |
Fasting glucose (mg/dL) | 111.00 (96.00–137.00) | 106.00 (96.75–129.50) | 118.00 (95.00–188.50) | 0.140 |
Blood urea nitrogen (mg/dL) | 16.00 (13.00–19.00) | 16.00 (13.00–18.00) | 17.00 (13.00–21.50) | 0.136 |
Creatinine (mg/dL) | 1.10 (0.90–1.30) | 1.00 (0.90–1.20) | 1.20 (0.90–1.45) | 0.054 |
Glomerular filtration rate (mL/min) | 68.73 ± 19.43 | 73.32 ± 17.35 | 62.26 ± 21.45 | 0.007* |
Total calcium (mg/dL) | 9.12 ± 0.35 | 9.14 ± 0.36 | 9.09 ± 0.35 | 0.503 |
Phosphorus (mg/dL) | 3.52 ± 0.54 | 3.53 ± 0.56 | 3.51 ± 0.51 | 0.804 |
Calcium-phosphorous product (mg2/dL2) | 32.16 ± 5.28 | 32.32 ± 5.55 | 31.89 ± 4.82 | 0.678 |
Intact parathyroid hormone (pg/mL) | 52.87 ± 26.81 | 52.73 ± 29.41 | 53.10 ± 21.70 | 0.944 |
Insulin (uIU/mL) | 11.90 (7.18–21.11) | 11.06 (6.69–19.85) | 13.02 (8.51–23.12) | 0.434 |
HOMA-IR | 3.67 (2.11–7.27) | 3.47 (1.81–7.06) | 4.00 (2.73–7.33) | 0.250 |
Female (%) | 28 (24.3) | 20 (27.0) | 8 (19.5) | 0.368 |
Diabetes (%) | 56 (48.7) | 27 (36.5) | 29 (70.7) | < 0.001* |
Hypertension (%) | 92 (80.0) | 56 (75.7) | 36 (87.8) | 0.119 |
Metabolic syndrome | 70 (60.9) | 40 (54.1) | 30 (73.2) | 0.044* |
Notes: Values for continuous variables given as means ± standard deviation and compared by Student’s t-test; variables not normally distributed given as medians and interquartile range and compared by Mann–Whitney U-test; values are presented as number (%), and analysis was performed using the chi-square test. *P < 0.05 was considered statistically significant.
Abbreviations: cfPWV, carotid-femoral pulse wave velocity; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; ARB, angiotensin-receptor blocker; ACE, angiotensin-converting enzyme; CCB, calcium-channel blocker.