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. 2019 Oct 8;12:2065–2073. doi: 10.2147/DMSO.S218718

Table 4.

Adjusted Hazard Ratios For A Composite End-Point Consisting Of First Hospitalization Based On A Multivariate Cox Regression Model For Aortic Arterial Stiffness In The 115 Coronary Artery Disease Patients With Or Without Metabolic Syndrome

Model 1 Model 2 Model 3
Hazard Ratio (95% CI) P value Hazard Ratio (95% CI) P value Hazard Ratio (95% CI) P value
No AS and no MS Reference Reference Reference
No AS and MS 2.48 (0.93–6.60) 0.069 2.17 (0.75–6.28) 0.151 2.38 (0.77–7.38) 0.134
AS and no MS 3.86 (1.12–13.28) 0.032* 5.48 (1.50–20.05) 0.010* 6.54 (1.67–25.68) 0.007*
AS and MS 7.38 (2.61–20.83) < 0.001* 8.23 (2.46–27.86) < 0.001* 10.20 (2.77–37.53) < 0.001*

Notes: Model 1 is adjusted for age, waist circumference, and body mass index. Model 2 is adjusted for the model 1 variables and for systolic blood pressure, triglycerides, high-density lipoprotein cholesterol, fasting glucose, insulin, and homeostasis model assessment of insulin resistance. Model 3 is adjusted for the model 2 variables and for blood urea nitrogen, creatinine, glomerular filtration rate, total calcium, phosphorus, and calcium-phosphorous product. *P < 0.05 was considered statistically significant.

Abbreviations: AS, arterial stiffness; MS, metabolic syndrome; CI, confidence interval.