Table 1.
Patient Characteristics
| Total (N=63) | |
|---|---|
| Age, years (median, range) | 62 (44–74) |
| Gender | |
| Male | 51 (81.0%) |
| Female | 12 (19.0%) |
| ECOG Performance Status | |
| 0 | 26 (41.3%) |
| 1 | 34 (54.0%) |
| 2 | 3 (4.8%) |
| Disease | |
| AML | 13 (20.6%) |
| MDS | 50 (79.4%) |
| IPSS (MDS Only) | |
| Low | 3 (7.3%) |
| Intermediate-1 | 9 (22.0%) |
| Intermediate-2 | 26 (63.4%) |
| High | 3 (7.3%) |
| Missing | 9 |
| N/A (AML Patients) | 13 |
| Cytogenetics Risk | |
| Normal | 29 (47.5%) |
| Complex | 18 (29.5%) |
| −7, del(7)q | 8 (13.1%) |
| Other | 6 (9.8%) |
| Missing | 2 |
| Induction Regimen | |
| 7+3 | 12 (20.3%) |
| DNA hypomethylating agent | 41 (69.5%) |
| Other | 2 (3.4%) |
| Unknown | 4 (6.8%) |
| No prior chemotherapy | 4 |
| Donor type | |
| MRD | 23 (36.5%) |
| MUD | 40 (63.5%) |
| Months from diagnosis to transplant, median (range) | 5.9 (1.8–109.7) |
| ABO Compatibility | |
| Match | 29 (46%) |
| Major mismatch | 12 (19%) |
| Minor mismatch | 19 (30.2%) |
| Bidirectional | 3 (4.8%) |
| Patient | Donor CMV serology | |
| Negative | Negative | 27 (42.9%) |
| Negative | Positive | 7 (11.1%) |
| Negative | Unknown | 1 (1.6%) |
| Positive | Negative | 8 (12.7%) |
| Positive | Positive | 19 (30.2%) |
| Positive | Unknown | 1 (1.6%) |
| Patient | Donor Gender | |
| Female | Female | 1 (1.6%) |
| Female | Male | 11 (17.5%) |
| Male | Female | 16 (25.4%) |
| Male | Male | 35 (55.6%) |
| Number of Cells Infused, CD34+ ×106/kg, median (range) | 5.0 (2.5–19.3) |