Table 2.
Gene expression results
| Gene | 2−ΔCt values | p value | ||||
|---|---|---|---|---|---|---|
| Drug free | 5‐ASA | Anti‐TNF | Controls | |||
| ABCB1 | 0.09 ± 0.06 | 0.11 ± 0.02 | 0.29 ± 0.11 | 0.42 ± 0.19 |
DF vs. anti‐TNF DF vs. CTRL 5‐ASA vs. CTRL |
0.023 <0.001 0.041 |
| LCN2 | 18.96 ± 4.48 | 6.84 ± 1.31 | 4.73 ± 1.22 | 0.71 ± 0.23 |
DF vs. anti‐TNF DF vs. CTRL 5‐ASA vs. CTRL Anti‐TNF vs. CTRL |
0.035 <0.001 <0.001 0.037 |
| NOS2 | 1.10 ± 0.28 | 0.42 ± 0.12 | 0.49 ± 0.12 | 0.06 ± 0.02 |
DF vs. CTRL DF vs. 5‐ASA 5‐ASA vs. CTRL Anti‐TNF vs. CTRL |
<0.001 0.034 0.007 0.003 |
| TFF1 | 6.54 ± 1.77 | 3.57 ± 0.56 | 1.63 ± 0.25 | 1.49 ± 0.38 |
DF vs. CTRL DF vs. anti‐TNF 5‐ASA vs. CTRL |
<0.001 0.009 0.016 |
Note. Levels of the transcripts (as 2−ΔCt values) differentially expressed among the groups. Genes are arranged in alphabetic order. CTRL = controls; DF = drug free.