Table 2.

Number of patients reporting side effects

Side effect (n(%))	Tapentadol group (n = 15)	Placebo group (n = 19)	p‐value
Nausea	11 (73)	4 (21)	0.005
Dizziness	4 (27)	4 (21)	1.000
Headache	3 (20)	10 (53)	0.079
Dry mouth	1 (7)	0 (0)	0.441
Somnolence	4 (27)	1 (5)	0.146
Itch	4 (27)	1 (5)	0.146
Constipation	5 (33)	2 (11)	0.199
Shortness of breath	2 (13)	0 (0)	0.187
Palpitations	1 (7)	0 (0)	0.441
Weariness	3 (20)	2 (11)	0.634
Sweating	2 (13)	0 (0)	0.187
Depressive symptoms	2 (13)	0 (0)	0.187
Euphoria	1 (7)	0 (0)	0.441
Blurred vision	1 (7)	0 (0)	0.441
Muscle cramps	1 (7)	0 (0)	0.441