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Cornea confocal microscopy
| All patients (n = 34) | TPT group (n = 15) | PLC group (n = 19) | |
|---|---|---|---|
| Abnormal CCM (n, %)a | 13 (38) | 7 (47) | 6 (32) |
| CNFD (n/mm2) | 15.3 | 14.7 | 15.8 |
| CNBD (n/mm2) | 20.7 | 18.8 | 22.3 |
| CNFL (n/mm2) | 13.6 | 13.4 | 13.8 |
Abbreviations: CCM, cornea confocal microscopy; CNBD, cornea nerve branching density; CNFD, cornea nerve fibre density; CNFL, cornea nerve fibre length; PLC, placebo; TPT, tapentadol.
Relative to reference value (Tavakoli et al., 2015).
