Gupta 2002.
| Methods | Randomised trial. Method of randomisation not stated. Single centre in New Delhi, India. Total duration of trial 1.5 to 2 years in both study groups. Ethical approval/consents not stated. |
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| Participants | 81 participants, 41 people with NCC treated for 6 months in group A, 40 people with NCC treated for a period of 12 months in group B. Diagnostic criteria based on CT Scan findings. Age and sex distribution not stated. Inclusion criteria: all patients with epilepsy and diagnostic CT findings, only patients with a single lesion. Exclusion criteria: suspected tuberculoma and NCC patients treated with albendazole. Follow‐up: 12 months after drug withdrawal. |
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| Interventions | AED treatment for seizure control for 6 months in group A and 12 months in group B. Details of drug used, dosage in either groups not stated. |
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| Outcomes | Seizure recurrence after stoppage of treatment. | |
| Notes | Single outcome studied. Withdrawls and exact number of excluded patients not stated. Choice of AED not mentioned. Dosage, side effects, cost and impact on quality of life not studied. | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Method of randomisation not detailed |
| Allocation concealment (selection bias) | Unclear risk | Exact methodology not detailed in the article |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | Not mentioned in article, probably not blinded |
| Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Method of outcome recording not stated |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Withdrawals, exclusions and reasons (if any) not stated |
| Selective reporting (reporting bias) | Unclear risk | Protocol not available. Insufficient information to comment on reporting |
| Other bias | High risk | AED used, formulation and dosage not stated in the article |