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Synthesis of 3. a) 1. HNEt2 (6 equiv.), CH2Cl2, −30 °C, −3 [H2NEt2]Cl; 2. NH3 (2 equiv.), CH2Cl2, −20 °C, −[NH4]Cl; 3. KOtBu, MeOH, 0 °C, −KCl, −HOtBu. b) H2NtBu (3 equiv.), n‐pentane, −2 [H3NtBu]Cl. c) 160 °C, 3 days. d) KOtBu, MeOH, 0 °C, −KCl, −HOtBu. e) NaNH2, NH3, −70 °C to rt, −NaCl, −NH3.
