Table 1.

Autophagy in 14 mo C57 and mdx mice.

	C57	mdx	p-Value
beclin 1	1.00 ± 0.04	0.95 ± 0.11	0.71
ATG5	1.00 ± 0.03	1.00 ± 0.07	0.98
ATG7	1.00 ± 0.03	1.02 ± 0.07	0.81
LC3I	1.00 ± 0.04	0.97 ± 0.13	0.83
LC3II	1.00 ± 0.20	0.44 ± 0.08a	0.02
LC3II/I	1.00 ± 0.22	0.59 ± 0.20	0.19
p62	1.00 ± 0.02	0.99 ± 0.03	0.76

Note: Markers of autophagy were largely similar except LC3II, a marker of autophagosome maturation, which was significantly decreased. Mean ± SEM.

^aSignificantly different from C57 controls (p < 0.05). C57 14 mo (n = 7) and mdx 14 mo (n = 7).