Table 1.
MicroRNA | Gene | SNP | Target is ancestral | EAS | AMR | AFR | EUR | SAS | All | Fst |
---|---|---|---|---|---|---|---|---|---|---|
miR-202-5p | ATP1A1 | rs1885802 | yes | 0.0427 | 0.1268 | 0.8109 | 0.0338 | 0.0450 | 0.2559 | 0.7914 |
miR-130a-3p | SLC30A9 | rs12511999 | yes | 0.0486 | 0.2363 | 0.9130 | 0.2495 | 0.2219 | 0.3773 | 0.7302 |
miR-513a | TCERG1 | rs3822506 | no | 0.7183 | 0.1167 | 0.0325 | 0.0915 | 0.2198 | 0.2307 | 0.7224 |
miR-151a-3p | MTAP | rs12003714 | no | 0.9921 | 0.9380 | 0.2042 | 0.9950 | 0.8824 | 0.7567 | 0.8638 |
let-7a-5p | MTAP | rs7875199 | yes | 0.0536 | 0.0576 | 0.7958 | 0.0070 | 0.1288 | 0.2555 | 0.7997 |
miR-24-3p | SCN2B | rs624328 | no | 0.9405 | 0.8905 | 0.2519 | 0.9513 | 0.9673 | 0.7601 | 0.7674 |
miR-192-5p | C12orf65 | rs1533703 | yes | 0.9980 | 0.7262 | 0.1490 | 0.7694 | 0.7945 | 0.6512 | 0.7074 |
miR-25/92a-3p | PTK6 | rs186332 | no | 0.9643 | 0.8732 | 0.0469 | 0.9284 | 0.5930 | 0.6304 | 0.8487 |
The target allele frequencies are provided for East Asian (EAS), Mixed American (AMR), African (AFR), European (EUR) and South Asian (SAS) populations, as described in the 1000 genomes project (see ‘Methods’ section).