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. 2019 Oct 14;14:175. doi: 10.1186/s13014-019-1378-x

Table 3.

Late toxicity in the second cohort from the assessment at the time of analysis

Toxicity CF-PMRT
n (%)
N = 457
HF-PMRT
n (%)
N = 480
p-value
Skina < 0.001
 Grade 0 197 (43) 340 (71)
 Grade 1 255 (56) 122 (25)
 Grade 2 5 (1) 9 (2)
 Grade 3 0 (0) 9 (2)
Subcutaneous tissuea < 0.001
 Grade 0 261 (57) 370 (77)
 Grade 1 185 (41) 75 (16)
 Grade 2 11 (2) 35 (7)
Lung (Clinical)a < 0.001
 Grade 0 389 (85) 239 (50)
 Grade 1 62 (14) 240 (50)
 Grade 2 6 (1) 1 (< 1)
Lung (Imaging)a < 0.001
 Grade 0 184 (40) 249 (52)
 Grade 1 199 (44) 187 (39)
 Grade 2 24 (5) 7 (1)
 Grade 3 50 (11) 37 (8)
Hearta 0.840
 Grade 0 453 (99) 477 (99)
 Grade 1 0 (0) 0 (0)
 Grade 2 1 (< 1) 0 (0)
 Grade 3 3 (< 1) 3 (< 1)
Lymphedemab 0.905
 Stage 0 442 (97) 467 (97)
 Stage 1 11 (2) 9 (2)
 Stage 2 4 (1) 4 (1)
Brachial Plexopathyc < 0.001
 Grade 0 421 (92) 469 (98)
 Grade 1 36 (8) 11 (2)

CF-PMRT Conventional fractionated post mastectomy radiotherapy, HF-PMRT Hypofractionated post mastectomy radiotherapy, N number

aRTOG/EORTC Late Radiation Morbidity Scoring Schema [11]

bISL [12]

cModified LENT SOMA scales [13]