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. 2019 Oct 14;19:266. doi: 10.1186/s12935-019-0981-0

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Inhibitory effects of the EGCG derivatives on NSCLC cells. a–e The inhibitory effects of compounds 1–5 on NCI-H441 (left panel), A549 (middle panel), and H1975 (right panel) cells, as evaluated by the MTT assay. f NCI-H441 cells were treated with compound 3 (100 μM) and cDDP (12 μM) in combination or individually, prior to the MTT assay. g, h Clonogenic assay of NCI-H441 cells treated with compound 3 (100 μM), cDDP (12 μM), or both. Data represent the average of three independent experiments (mean ± SD, p < 0.001). ***p < 0.001, cDDP + compound 3 vs cDDP; ^###p < 0.001, cDDP + compound 3 vs compound 3