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. 2019 Sep 15;39(12):1475–1487. doi: 10.1177/0333102419876920

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© International Headache Society 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Changes in number of headache days over time for (a) the ITT population and (b) the mITT population.

^aThe nVNS and sham groups were compared using ANCOVA models; p-values were derived from linear regression adjusted for treatment group, centre, presence/absence of aura (based on diagnosis provided in subject medical history at enrolment), and number of migraine days in the run-in period.

ANCOVA: analysis of covariance; CI: confidence interval; ITT: intent-to-treat; nVNS: non-invasive vagus nerve stimulation.