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. 2019 Sep 8;22(1):106–114. doi: 10.22074/cellj.2020.6537

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The Cell Journal (Yakhteh) is an open access journal which means the articles are freely available online for any individual author to download and use the providing address. The journal is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported License which allows the author(s) to hold the copyright without restrictions that is permitting unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig.5 — Alteration in gene expression and protein production under simulated microgravity. A. After five days, MAPK1 showed significant up-regulation in the both adherent cells and spheroids under simulated microgravity (3.2x and 3.0 respectively, *P<0.05 each). Gene up-regulation was confirmed on protein level by western blot and B. VEGF was down-regulated under simulated microgravity in both gene expression and protein levels, but the values were not statistically significant.