Table 2.
Effect of different levels of independent variables on the weight, thickness, gel fraction, swelling ratio, folding, absorbance protein, water vapor transmission rate, production, drug content and flux.
| F | Variable levels | W (g) | T (mm) | GF (%) | SI (%) | Pr (mg/mL) | F (n) | WVTR (%) | PY (%) | DC (%) | Flux (mg/cm2/min) * 10-5 | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| X1 | X2 | X3 | X4 | |||||||||||
| F6 | 1000 | 5 | 0.75 | 3 | 0.027 | 0.207 | 64 | 61. | 269.6 | > 300 | 0 | 103 | 20.52 | 2 |
| F7 | 750 | 7.5 | 0.5 | 5 | 0.018 | 0.195 | 57.9 | 61.2 | 439.1 | > 300 | 0 | 97 | 20.50 | 2 |
| F17 | 1000 | 5 | 1 | 5 | 0.036 | 0.257 | 72 | 58.7 | 173.9 | > 300 | 0 | 92.62 | 26 | 3 |
| F21 | 750 | 5 | 1 | 7 | 0.026 | 0.166 | 37.8 | 65.6 | 126.1 | > 300 | 0 | 81.60 | 17.04 | 2 |
X1, drug amount; X2, amount of polyvinyl alcohol; X3, amount of chitosan; X4, freeze-thaw cycle; W, Weight; T, thickness; GF, gel fraction; SI, swelling index; F, folding; Pr, absorbance of protein onto hydrogel surface; WVTR, water vapor transmission rate; PY, production; DC, drug content.