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. 2019 Mar 8;14(2):138–145. doi: 10.4103/1735-5362.253361

Table 1.

Effects of Ferula Gummosa oleo-resin on the body weight, food intake, water intake, and the weight of liver and kidneys of diabetic rats. Values are expressed as mean ± SEM (n = 6). Significant differences were observed (*P < 0.01 and ***P < 0.001, respectively) in comparison with normal control; # and ## show significant differences (P < 0.05 and P < 0.01, respectively) versus diabetic control; and × shows significant differences (P < 0.01) versus day 1 in the corresponding group.

Parameters Time Normal control Diabetic control Insulin-treated diabetes F. gummosa-treated diabetes (100 mg/kg) F. gummosa-treated diabetes (400 mg/kg)
Body weight (g) Day 1 253 ± 7 230 ± 11 237 ± 5 248 ± 4 242 ± 8
Week 4 (weight gain) 303 ± 8× (+20%) 187 ± 13*× (-19%) 278 ± 6##× (+17%) 213 ± 4*#× (-14%) 210 ± 10*× (-13%)
Food intake (g/24 h) Week 4 21 ± 1 37 ± 2.5* 33 ± 2.5* 39 ± 2* 38 ± 1.5*
Water intake (mL/24 h) Week 4 56 ± 4 122 ± 10* 98 ± 10*# 105 ± 5* 100 ± 13*
Liver weight (g) Week 4 11.2 ± 0.6 8.1 ± 0.4*** 11.8 ± 0.84## 10.1 ± 0.2 10.4 ± 0.5#
Kidney weight (g) Week 4 1 ± 0.04 1.02 ± 0.06 1.06 ± .06 1.15 ± .03 1.08 ± 0.06