Table 2.
Effects of Ferula Gummosa oleo-resin on the levels of FBG and serum lipids of diabetic rats. Values are expressed as mean ± SEM (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001 versus normal control; #P < 0.05 versus diabetic control.
| Parameters | Normal control | Diabetic control | Insulin-treated diabetes | F. gummosa-treated diabetes (100 mg/kg) | F. gummosa-treated diabetes (400 mg/kg) |
|---|---|---|---|---|---|
| FBG Day 1 (mg/dL) | 99 ± 5 | 346 ± 39*** | 393 ± 20*** | 300 ± 21*** | 326 ± 23*** |
| FBG Week 4 (mg/dL) | 97 ± 11 | 421 ± 56*** | 299 ± 65* | 275 ± 60*# | 349 ± 57** |
| Changes related to day 1 | -2% | +22% | -24% | -8% | +7% |
| Triglyceride (mg/dL) | 56 ± 11 | 72 ± 15 | 55 ± 16 | 55 ± 15 | 60 ± 12 |
| Total cholesterol (mg/dL) | 65 ± 4 | 96 ± 8** | 88 ± 5** | 76 ± 6 | 82 ± 7* |
| LDL (mg/dL) | 14 ± 1 | 26 ± 9* | 21.5 ± 3.5 | 16.5 ± 1.3 | 18 ± 1.5 |
| HDL (mg/dL) | 45 ± 4 | 38 ± 2 | 44 ± 2 | 42 ± 2 | 45 ± 3 |
F. gummosa, Ferula Gummosa; FBG, fasting blood glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein.