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SHMT2 promoted the proliferation and invasion of GC cells. (A) Successful knockdown of SHMT2 in MKN-28 cells by siRNA was detected with Western blot. (B) CCK-8 assay was used to detect the proliferation of MKN-28 cells. SHMT2 knockdown notably attenuated the proliferation of MKN-28 cells. (C) Cell invasion was detected by Matrigel Transwell assay. SHMT2 knockdown decreased the invasion of MKN-28 cells.
