Table 3.

Characteristics of the p53 mutants in vivo

p53	E6-dependent degradationa	Subcellular distributionb	Transactivationc
WT	+	Nucleus	+
14KR	+	Nucleus	+
14+4KR	−	Nucleus/cytoplasm	−
13(1)+4KR	−	Nucleus/cytoplasm	−
13(2)+4KR	−	Nucleus/cytoplasm	−
12+4KR	−	Nucleus	−

^a Data are shown in Fig. 8A and Fig. S5.

^b Data are shown in Fig. S6.

^c Data are shown in Fig. 8 (B–D).