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FPR1 Antagonist Activity of Methionine-derived Benzimidazoles 93-104 [84]
 | |||
|---|---|---|---|
| # | IC50(μM)a | # | IC50 (μM) |
| 93 | 0.5 | 99 | 2.5 |
| 94 | 4.0 | 100 | 0.32 |
| 95 | 4.0 | 101 | 5.0 |
| 96 | 2.5 | 102 | 3.2 |
| 97 | 5.0 | 103 | 0.63 |
| 98 | 2.0 | 104 | <25 |
Inhibition of fMLF-stimulated intracellular Ca2+ flux in human neutrophils; IC50 values were recalculated from reported pIC50 values.
