Table 2.

Comparisons of diagnostic models and protein markers in different cohorts.

Group	Variable	AUC	95% CI	p value
Training Group	CEA	0.835	0.772–0.898	0.0081
(n = 158)	CA125	0.728	0.649–0.807	<0.0001
	Primary Model	0.897	0.848–0.946	/
	Second Model	0.846	0.785–0.907	0.0061
Validation Group	CEA	0.769	0.695–0.842	0.0031
(n = 158)	CA125	0.736	0.659–0.813	0.0024
	Primary Model	0.856	0.798–0.914	/
	Second Model	0.797	0.727–0.866	0.0265
Whole Group	CEA	0.797	0.749–0.846	0.0005
(n = 316)	CA125	0.729	0.674–0.784	<0.0001
	Primary Model	0.866	0.826–0.905	/
	Second Model	0.814	0.768–0.861	0.0025

Abbreviations: CEA = carcinoembryonic antigen, CA125 = cancer antigen 125, AUC = area under the curve, 95%CI = 95% Confidence Intervals.