Table 1.
Clinicopathological characteristics of ACC patients.
| Characteristics | N (%) | |
|---|---|---|
| Age, median | years (range) | 49 (14–77) |
| Sex | female | 48 (61%) |
| male | 31 (39%) | |
| ENSAT stage | 1 | 9 (12%) |
| 2 | 37 (48%) | |
| 3 | 16 (21%) | |
| 4 | 15 (19%) | |
| Pathological tumor size (pT) | pT1 | 9 (12%) |
| pT2 | 42 (55%) | |
| pT3 | 8 (10%) | |
| pT4 | 18 (23%) | |
| Pathological lymph node (pN) | pN0 | 68 (88%) |
| pN1 | 9 (12%) | |
| Surgical margins status | R0 | 55 (79%) |
| R1 | 6 (9%) | |
| R2 | 9 (13%) | |
| Weiss classification | low (1–3) | 14 (22%) |
| high (4–9) | 50 (78%) | |
| Steroid hormone secretion excess | no | 26 (35%) |
| yes | 48 (65%) | |
| Adjuvant mitotane | no | 4 (9%) |
| yes | 39 (91%) | |
| Adjuvant radiotherapy | no | 59 (79%) |
| yes | 16 (21%) | |
| TP53 mutation status | wild type | 64 (81%) |
| mutated | 15 (19%) | |
| MKI67 mRNA status | low | 40 (51%) |
| high | 39 (49%) | |
| DFS event* | 27 (42%) | |
| 5-year DFS* | 52% [39–70] | |
| *, M0 patients only (N = 64) | ||