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. 2019 May 8;127(5):057003. doi: 10.1289/EHP3915

Table 2.

Associations (hazard ratios [95% confidence intervals]) between individuals living in households using solid fuels for cooking, compared with clean fuels, and cause-specific mortality, CVD, and respiratory disease during a median of 9.1-y follow-up.

Health outcome Events Model 1 (base model) Model 2 (+risk factors) Model 3 (+SES)
All-cause mortality 6,595 1.24 (1.15, 1.33) 1.24 (1.16, 1.34) 1.12 (1.04, 1.21)
Cause-specific mortalitya
 CVD 2,104 1.08 (0.95, 1.22) 1.18 (1.04, 1.34) 1.04 (0.91, 1.19)
 Respiratory 356 1.82 (1.32, 2.51) 1.54 (1.11, 2.12) 1.34 (0.95, 1.89)
 Cancer 1,126 1.26 (1.06, 1.49) 1.22 (1.03, 1.45) 1.15 (0.96, 1.38)
 Other causes 1,034 1.50 (1.22, 1.84) 1.49 (1.21, 1.84) 1.25 (1.00, 1.55)
 Injury 393 1.39 (1.03, 1.87) 1.31 (0.97, 1.77) 1.24 (0.89, 1.72)
 Not classified 1,544 1.21 (1.05, 1.40) 1.17 (1.01, 1.35) 1.07 (0.91, 1.25)
CVD (fatal+nonfatal)b 5,472 1.06 (0.98, 1.14) 1.14 (1.05, 1.23) 1.08 (0.99, 1.17)
 MI 2,363 1.01 (0.90, 1.13) 1.12 (1.00, 1.26) 1.07 (0.94, 1.22)
 Stroke 2,685 1.12 (1.00, 1.26) 1.16 (1.03, 1.30) 1.12 (0.99, 1.27)
 Heart failure 476 1.10 (0.84, 1.43) 1.20 (0.92, 1.56) 1.13 (0.85, 1.50)
CVD hospitalizationc 4,407 1.05 (0.96, 1.15) 1.14 (1.04, 1.25) 1.10 (1.00, 1.22)
Respiratory disease (fatal+nonfatal)d 2,436 1.29 (1.14, 1.46) 1.24 (1.10, 1.41) 1.14 (1.00, 1.30)
 TB 530 1.68 (1.26, 2.23) 1.48 (1.11, 1.96) 1.29 (0.95, 1.74)
 COPD 708 1.31 (1.05, 1.63) 1.28 (1.02, 1.59) 1.15 (0.91, 1.44)
 Pneumonia 893 1.17 (0.95, 1.44) 1.20 (0.98, 1.48) 1.17 (0.94, 1.46)
 Lung cancer 239 0.84 (0.58, 1.24) 0.83 (0.57, 1.22) 0.79 (0.53, 1.18)
Respiratory hospitalizatione 1,517 1.30 (1.11, 1.52) 1.29 (1.10, 1.51) 1.17 (0.98, 1.38)
Incident cardiorespiratory disease+all -cause mortalityf 11,111 1.18 (1.12, 1.25) 1.20 (1.14, 1.27) 1.12 (1.06, 1.19)
Asthmag 693 1.15 (0.93, 1.43) 1.05 (0.84, 1.31) 0.88 (0.69, 1.11)
Injuryh 3,461 1.05 (0.94, 1.16) 1.05 (0.94, 1.17) 1.01 (0.90, 1.14)
Injury hospitalization 1,213 1.16 (0.98, 1.37) 1.15 (0.97, 1.36) 1.02 (0.85, 1.22)

Model 1: Age, sex, baseline year, strata for center and urban/rural status.

Model 2: Model  1+INTERHEART risk score, smoking, physical activity, alcohol use, alternative healthy eating index, BMI, baseline chronic condition, baseline CVD medication use, baseline hypertensive status, outdoor PM2.5.

Model 3: Model  2+education, percentage income spent on food, and strata for household wealth index tertile.

a

Cause-specific death.

b

Fatal and nonfatal myocardial infarction, stroke, and heart failure.

c

Documented hospitalization for myocardial infarction, stroke, or heart failure.

d

Fatal and nonfatal COPD, pneumonia, tuberculosis, and lung cancer.

e

Documented hospitalization for COPD, pneumonia, tuberculosis, and lung cancer.

f

Composite outcome: mortality from any cause or the first incidence of any major nonfatal CVD (MI, stroke, HF) or respiratory outcome (tuberculosis, COPD, pneumonia, or lung cancer, but not asthma) as an indicator of all health outcomes likely related to HAP.

g

Physician diagnosis of asthma. Not included as a major respiratory disease outcome due to lack of evidence for association with HAP.

h

Fatal or nonfatal injury. Hospitalizations refer to injuries with a documented hospital admission.