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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Crit Care Med. 2019 Nov;47(11):e930–e938. doi: 10.1097/CCM.0000000000003967

Figure 3. 3D 6-Acyl PHAD enhances phagocytosis and respiratory burst in primary innate leukocytes.

Figure 3.

Mice received vehicle or 20 μg of 3D 6-Acyl PHAD via IP injection 48 and 24 hours prior to assessing phagocytic function and respiratory burst. (A) Phagocytic function was assessed by IP injection of 500 μg pH Rodo Red S. aureus particles, followed by a 6 hour incubation period. Peritoneal lavage cells were examined using flow cytometry. pH Rodo MFI represents the degree of phagocytosis per cell. Results represent 4 separate experiments, n=16–20 per group. (B) Respiratory burst function of peritoneal lavage cells was assessed following induction of respiratory burst with PMA. Respiratory burst capacity was assessed by DHR 123 MFI. Results represent 2 separate experiments, n=4 per group.