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. 2019 Sep 17;20(11):1498–1514. doi: 10.3348/kjr.2019.0155

Table 1. Summary of CT-Guided Localization Techniques according to Materials Used.

Methods Advantages Disadvantages
Hook-wire Simple and most commonly used methods Patient discomfort or pain because of wire
No need for fluoroscopic guidance during surgery Risk of wire dislodgement or migration
Risk of air embolism
Microcoil or spiral coil Can safely remain in body for relative long time Need fluoroscopic guidance during surgery for coil detection
Reduced patient discomfort or pain compared to hook-wire Risk of migration
Does not interfere histopathologic examination
Lower procedure related complication rate compared to hook-wire
Dye (methylene blue or indigo carmine) Simple and less costly methods than wire-related techniques Rapid dye diffusion: Localization must be performed within 3 hours before surgery
No need for fluoroscopic guidance during surgery Limited information on lesion depth
Difficulty in identifying dye in case of extensive anthracotic pigmentation
Barium Simple and less costly methods than wire or coil techniques Can affect pathologic diagnosis because of inflammatory response
Remain stable in body for relative long time without diffusion Need fluoroscopic guidance during surgery
Provide information on lesion depth
Lipiodol Simple and easy methods Need fluoroscopic guidance during surgery
Remain stable in body for relative long time without diffusion Risk of spillage to pleural space
Do not cause inflammatory response in pathologic tissue
Provide information on lesion depth
Radiotracer (technetium-99m) Simple and less costly methods Short half-life (about 6 hours)
Remain stable in body for longer time (1 day) than dye Needs gamma probe
Radiation exposure
Risk of spillage to pleural space