Table 2.
High confidence interacting partners/substrates of cyclin F. Data shown correspond to MASCOT protein outputs including: protein score, N. Significant sequences and emPAI value
| Name | Cyclin F | Empai | Cyclin F + MLN4924 | Empai | ||
|---|---|---|---|---|---|---|
| Score | No.sign peptides | Score | No.sign peptides | |||
| Cyclin F (F‐box only protein 1) | 1,973 | 18 | 2.04 | 1,993 | 28 | 5.39 |
| Cell division control protein 6 homolog (CDC6‐related protein) (Cdc18‐related protein) (HsCdc18) [p62(cdc6)] (HsCDC6) | 107 | 3 | 0.25 | 193 | 9 | 0.95 |
| M‐phase phosphoprotein 9 | 56 | 2 | 0.07 | 162 | 8 | 0.33 |
| Geminin | 52 | 1 | 0.22 | 247 | 8 | 7.88 |
| Ankyrin repeat domain‐containing protein 17 (gene trap ankyrin repeat protein) (serologically defined breast cancer antigen NY‐BR‐16) | 51 | 1 | 0.02 | 100 | 5 | 0.09 |
| Zinc finger protein 318 (endocrine regulatory protein) | 50 | 3 | 0.06 | 126 | 8 | 0.16 |
| Exonuclease 1 (hExo1) (EC 3.1.‐.‐) (exonuclease I) (hExoI) | 50 | 2 | 0.1 | 113 | 6 | 0.35 |
| Protein red (cytokine IK) (IK factor) (protein RER) | 45 | 1 | 0.07 | 53 | 2 | 0.15 |
| DNA replication factor Cdt1 (double‐parked homolog) (DUP) | 71 | 2 | 0.17 | 140 | 10 | 1.17 |
| Opioid growth factor receptor (OGFr) (protein 7‐60) (zeta‐type opioid receptor) | 60 | 1 | 0.07 | 37 | 1 | 0.07 |
| Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) | 59 | 1 | 0.13 | 41 | 1 | 0.13 |
| Cullin‐1 (CUL‐1) | 53 | 2 | 0.11 | 91 | 3 | 0.17 |
| Ribonucleoside‐diphosphate reductase subunit M2 (EC 1.17.4.1) (ribonucleotide reductase small chain) (ribonucleotide reductase small subunit) | 1 | 0 | 0 | 61 | 1 | 0.11 |
| Treslin (TopBP1‐interacting checkpoint and replication regulator) (TopBP1‐interacting, replication‐stimulating protein) | 31 | 1 | 0.02 | 68 | 2 | 0.05 |
| Casein kinase II subunit alpha 3 (CK II alpha 3) (EC 2.7.11.1) (casein kinase II alpha 1 polypeptide pseudogene) | 1 | 0 | 0 | 50 | 1 | 0.12 |
| BRISC and BRCA1‐A complex member 1 (mediator of RAP80 interactions and targeting subunit of 40 kDa) (new component of the BRCA1‐A complex) | 45 | 1 | 0.14 | 1 | 0 | 0 |
| Zinc finger protein 8 (zinc finger protein HF.18) | 1 | 0 | 0 | 39 | 3 | 0.24 |
| Protein aurora borealis (HsBora) | 1 | 0 | 0 | 38 | 2 | 0.17 |
| Mdm2‐binding protein (hMTBP) | 1 | 0 | 0 | 46 | 1 | 0.05 |
| Transcription factor E2F3 (E2F‐3) | 1 | 0 | 0 | 42 | 1 | 0.1 |
| Transcription factor ETV6 (ETS translocation variant 6) (ETS‐related protein Tel1) (Tel) | 1 | 0 | 0 | 37 | 1 | 0.09 |