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. 2019 Oct 8;10:962. doi: 10.3389/fgene.2019.00962

Figure 1.

Figure 1

Summary of critical time points and epigenetic events during the histone-to-protamine transition. The haploid germ cells undergo a dramatic morphological change, and nuclear chromatin re-organization starts from round spermatid (Spd) to mature spermatozoa. Detailed studies of the indicated histone variants and histone modification might establish the precise epigenetic events of spermiogenesis.