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. 2019 Oct 8;10:933. doi: 10.3389/fgene.2019.00933

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Copyright © 2019 Plotnikova, Baranova and Skoblov

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detailed analysis of experimentally confirmed microRNA-binding regions (Exp-MiBRs). (A) Validation of the Exp-MiBR by their independent occurrence in two or more datasets, or in two or more chimeric sequences from one dataset. (B) Exp-MiBRs: distribution of the lengths. On horizontal axis—the length of the Exp-MiBRs subsequence; on vertical axis—amounts of the detected Exp-MiBRs (N). (C). Venn diagram depicting Exp-MiBRs detected in experiments employing three different types of identification techniques. (D) Venn diagram depicting tissue specificity of Exp-MiBRs detected in HEK293, Huh7.5, and all other cell lines.