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. 2019 Jun 21;113(10):632–640. doi: 10.1093/trstmh/trz049

Table 3.

Force of infection across different age groups along with latent TB infection

Test Age, y N Mean (μ) Number of positive (%) OR (95% CI) Force of infection
TST≥5 mm <6 74 3.2 25 (34) 0.51 (0.32 to 0.83) 0.049
6–14 177 10.0 78 (44) 0.79 (0.59 to 1.06) 0.192
15–18 77 16.4 41 (53) 1.14 (0.73 to 1.78) 0.328
19–45 510 31.9 291 (57) 1.33 (1.12 to 1.58) 0.216
>45 139 54.9 94 (68) 2.09 (1.46 to 2.98) 0.138
Total 977 27.8 529 (54) 0.158
p-value 0.050
QFT-GIT <6 72 3.2 25 (35) 0.53 (0.33 to 0.86) 0.442
6–14 164 10.0 62 (38) 0.61 (0.44 to 0.83) 0.360
15–18 78 16.4 46 (59) 1.44 (0.92 to 2.26) 0.806
19–45 497 31.9 286 (58) 1.36 (1.13 to 1.62) 0.483
>45 134 54.9 92 (69) 2.19 (1.52 to 3.16) 1.094
Total 945 27.8 511 (54) 0.571
p-value 0.059
LTBI <6 80 3.2 38 (48) 0.90 (0.58 to 1.40) 0.438
6–14 182 10.0 97 (53) 1.14 (0.85 to 1.53) 0.363
15–18 79 16.4 61 (77) 3.39 (2.00 to 5.73) 0.696
19–45 525 31.9 408 (78) 3.49 (2.84 to 4.28) 1.153
>45 142 54.9 121 (85) 5.76 (3.63 to 9.16) 1.254
Total 1008 27.8 725 (72) 0.820
p-value 0.052

Force of infection: calculated at specific ages for the pool of individuals who remained uninfected (absolute change in prevalence/[1-baseline prevalence]); LTBI, latent TB infection; N, total participants; OR was calculated by considering all other subgroups as reference; QFT-GIT, Quantiferon-Gold In tube test; TST, tuberculin skin test.