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. 2019 Sep 13;10(10):1443–1449. doi: 10.1021/acsmedchemlett.9b00243

Figure 1.

Figure 1

(A) Chemical structure of BI-2536. (B) Surface representation of BI-2536-BRD4(1) cocrystal structure (4O74).29 (C) Cartoon cutaway of view as in (B) showing conserved waters (spheres), key residues (sticks), and H-bonding (dashed).