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. 2019 Sep 6;10(10):1386–1392. doi: 10.1021/acsmedchemlett.9b00301

Table 2. In Vitro Cytotoxicities of Unconjugated Compounds against HSC-2 and Namalwa/luc (NL) Cells.

  cell line IC50, M
compound HSC-2 NLa
DXd (4) 1 × 10–9 6 × 10–10
11 2 × 10–9 9 × 10–10
12 5 × 10–10 2 × 10–10
13 4 × 10–10 2 × 10–10
14b 6 × 10–10 2 × 10–10
a

Namalwa/luc cells (NL).