Table 6.

Associations between PM exposure and gene expression levels in 16-y-old children of the BAMSE cohort ($n=244$).

Chr	Gene	ProbeID	LogFC	p-Value
Concurrent ${\mathrm{PM}}_{10}$
6	NOTCH4	TC6_mcf_hap5000165.hg.1	0.05	9.52E-05
6	NOTCH4	TC6_apd_hap1000098.hg.1	0.06	9.73E-05
6	NOTCH4	TC6_mann_hap4000155.hg.1	0.06	9.98E-05
6	NOTCH4	TC6_cox_hap2000190.hg.1	0.05	1.03E-04
6	NOTCH4	TC6_ssto_hap7000159.hg.1	0.05	1.10E-04
6	NOTCH4	TC06001564.hg.1	0.05	1.31E-04
6	NOTCH4	TC6_qbl_hap6000179.hg.1	0.05	1.42E-04
17	USP43	TC17000146.hg.1	0.05	4.98E-04
4	FAM13A	TC04001380.hg.1	$-0.01$	2.14E-01
3	SRPRB	TC03000725.hg.1	$-0.01$	2.89E-01
Concurrent ${\mathrm{PM}}_{2.5}$
7	C7orf50	TC07001077.hg.1	0.02	0.03
19	PSG5	TC19001582.hg.1	0.02	0.06
1	VANGL2	TC01001369.hg.1	0.02	0.08
1	ZNF695	TC01006392.hg.1	0.01	0.08
8	COL22A1	TC08001675.hg.1	0.02	0.10
8	PLAT	TC08001175.hg.1	0.02	0.16
19	MRI1	TC19000239.hg.1	$-0.01$	0.17
2	CAPN10	TC02005015.hg.1	0.01	0.21
10	MKX	TC10001133.hg.1	0.01	0.29
13	TMCO3	TC13000425.hg.1	$-0.01$	0.30
7	PLXNA4	TC07001877.hg.1	0.01	0.33
19	ZNF606	TC19001910.hg.1	$-0.0003$	0.96

Note: Results presented per $5.6{\mathrm{\mu }\mathrm{g}/\mathrm{m}}^3$ increase in ${\mathrm{PM}}_{10}$ and $2{\mathrm{\mu }\mathrm{g}/\mathrm{m}}^3$ increase in ${\mathrm{PM}}_{2.5}$ exposure for genes annotated to FDR significant CpGs in the discovery ${\mathrm{PM}}_{10}$ and ${\mathrm{PM}}_{2.5}$ EWAS. $\text{LogFC}=\text{logarithm fold -change}$ (one unit of the logFCs translates to a two-fold change in expression). Adjusted for sex, maternal smoking during pregnancy, active smoking at the time of biosampling, age at biosampling, municipality at birth, doctor’s diagnosis of asthma, and cell composition.