Table 2.

Enrichment of molecular function and cellular component GO-terms in BA and CCA ECs. Top 5 GO molecular function and cellular component terms higher expressed in the BA compared to the CCA and vice versa. FDR is false discovery rate.0020

Gene set enrichment analysis on GO molecular function terms
Top 5 GO-terms higher expressed in basilar artery compared to carotid artery
G0-term	Molecular function	P-value	FDR
GO:0003735	STRUCTURAL_CONSTITUENT_OF_RIBOSOME	6.27E-07	3.51E-04
GO:0003743	TRANSLATION_INITIATION_FACTOR_ACTIVITY	9.51E-06	2.31E-03
GO:0044822	POLY_A_RNA_BINDING	7.67E-05	9.26E-03
GO:0016675	OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_HEME_GROUP_OF_DONORS	2.00E-04	1.65E-02
GO:0045182	TRANSLATION_REGULATOR_ACTIVITY	2.11E-04	1.67E-02
Top 5 GO-terms higher expressed in carotid artery compared to basilar artery
G0-term	Molecular function	P-value	FDR
GO:0042605	PEPTIDE_ANTIGEN_BINDING	6.42E-05	8.68E-03
GO:0008329	SIGNALING_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY	4.08E-04	2.55E-02
GO:0004896	CYTOKINE_RECEPTOR_ACTIVITY	8.94E-04	3.92E-02
GO:0001653	PEPTIDE_RECEPTOR_ACTIVITY	1.24E-03	4.74E-02
GO:0004115	3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY	1.40E-03	5.10E-02
Gene set enrichment analysis on GO cellular component terms
Top 5 GO-terms higher expressed in basilar artery compared to carotid artery
G0-term	Cellular component	P-value	FDR
GO:0044391	RIBOSOMAL_SUBUNIT	8.67E-08	1.02E-04
GO:0022626	CYTOSOLIC_RIBOSOME	9.69E-08	1.02E-04
GO:0015934	LARGE_RIBOSOMAL_SUBUNIT	1.65E-07	1.39E-04
GO:0005840	RIBOSOME	2.92E-07	2.02E-04
GO:0015934	CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT	2.99E-07	2.02E-04
Top 5 GO-terms higher expressed in carotid artery compared to basilar artery
G0-term	Cellular component	P-value	FDR
GO:0042611	MHC_PROTEIN_COMPLEX	1.90E-06	7.49E-04
GO:0042613	MHC_CLASS_II_PROTEIN_COMPLEX	5.47E-05	8.05E-03
GO:0032281	AMPA_GLUTAMATE_RECEPTOR_COMPLEX	2.00E-04	1.65E-02
GO:0061702	INFLAMMASOME_COMPLEX	3.85E-04	2.49E-02
GO:0005858	AXONEMAL_DYNEIN_COMPLEX	4.33E-04	2.63E-02